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Read your MTHFR, straight from your DNA.

The NuLevels Methylation Report turns your AncestryDNA or 23andMe raw data into a plain-language read on your MTHFR variants, the gene that shapes how well your body activates folate. Your DNA file is processed in your browser and never uploaded.

Processed on your device. No upload, no account required to read it.

Soft morning light over a wooden table

What the report tells you.

MTHFR is a gene that helps convert dietary folate and synthetic folic acid into 5-MTHF, the active form your body uses for methylation. Common variants (C677T and A1298C) can lower that conversion. The NuLevels Methylation Report reads those two variants from your raw DNA file and explains, in plain language, what they mean for the forms of folate and B12 worth discussing with your clinician.

It is educational, not a diagnosis. A genotype is a predisposition; the functional readout is bloodwork. Pair this with the methylation markers in our Testing Hub and a conversation with your clinician.

How it works.

No new test to buy if you have already taken a DNA test. If not, AncestryDNA is the cheapest reliable source.

1
Get your raw DNA data.
Already did AncestryDNA or 23andMe? Download your raw data file (a .txt) from your account. New to it? AncestryDNA is about $99 and gives you the file you need.
2
Upload it here.
Drop the .txt file into the box below. It is read in your browser. The file never leaves your device and we never store it.
3
Read it and act on it.
Get an instant on-screen report with a PDF to share with your doctor. If a variant is found, your NuRecord flags folic-acid supplements in your stack to review.

What it costs.

About $99 to $120
All in, most of which is the one-time DNA test itself.
  • AncestryDNA test kit, about $99 one time (or use a DNA file you already have)
  • NuLevels Methylation Report: read your MTHFR C677T and A1298C variants
  • Plain-language interpretation plus a print-ready PDF for your doctor
  • Automatic folic-acid flagging in your NuRecord supplement stack
I have my raw data, read it now

Upload your raw data.

AncestryDNA or 23andMe .txt file. Read privately, in your browser.

Your file is parsed locally and never uploaded or stored.

This tool reads two MTHFR variants (C677T / rs1801133 and A1298C / rs1801131) from a consumer DNA raw data file. It is educational and is not medical advice, a diagnosis, or a substitute for clinical genetic testing. A genotype indicates a predisposition, not a present deficiency; the functional readout is bloodwork such as homocysteine, active B12, and folate. Do not start, stop, or change any supplement or medication based on this report alone. Always confirm with your clinician.

Common questions.

Is my DNA data uploaded anywhere?
No. The file is read and interpreted entirely in your browser using JavaScript. Nothing is sent to our servers and nothing is stored. You can confirm this in your browser network tools: reading your file makes no upload request.
Which files work?
The raw data .txt download from AncestryDNA or 23andMe. If your download is a .zip, unzip it first and upload the .txt inside. We look for the MTHFR markers rs1801133 (C677T) and rs1801131 (A1298C).
I do not have a DNA test yet. What do I buy?
AncestryDNA is the cheapest reliable source at about $99, and its raw data export includes the MTHFR markers this report reads. You only buy the DNA test once; the methylation read is included here at no extra charge.
What does a positive result mean?
It means you carry one (heterozygous) or two (homozygous) copies of a common MTHFR variant, which is associated with reduced folate activation. It is a predisposition, not a diagnosis. The next step is bloodwork (homocysteine, active B12, folate) and a conversation with your clinician, not a change made on your own.
How does this connect to my supplements?
If a variant is found, you can record it in your NuRecord health profile. NuRecord then flags any folic-acid-containing supplements you have photographed, so you can review whether an active form like methylfolate (L-5-MTHF) is a better fit with your clinician. Methylfolate products are not flagged.
Upload your raw data